Platform

Science & Technology

Our platform targets the Warburg effect and VDAC/HK2 interactions at the heart of cancer metabolism.

Vidac Pharma's scientific platform is based on a novel approach to cancer metabolism — targeting the Warburg effect and selectively modulating VDAC/HK2 protein interactions unique to cancer cells.

Immuno-metabolism platform technology

Metabolic re-programming to aerobic glycolysis, known as the Warburg effect, allows cancer cells and some types of activated immune cells (e.g., macrophages and

VDAC/HK2 Modulators

Vidac Pharma’s small molecule drug candidates are allosteric protein-protein interaction disrupters. Given the importance of the HK2-VDAC association for the pr

Association of HKs to VDAC

Both HK1 and HK2 attach to the mitochondria via interaction with the voltage-dependent anion channel 1 (VDAC1) on the cytosolic side of the outer mitochondrial

HK2 in Cancer

One of the key characteristics of cancer cells is their increased rate of glucose uptake and breakdown, a process known as glycolysis. Cancer cells utilize glyc